Archives : Oct, 2012
Numerical Study on Platelet Adhesion to Vessel Walls using the Kinetic Monte Carlo Method
Abstract:
The interaction between platelets and vessel walls in the primary aggregation of platelets was investigated using kinetic Monte Carlo simulation for the multiscale simulation of thrombus formation. The kinetic Monte Carlo lattice model of a platelet surface with glycoprotein Ibα (GPIbα) localization region was simulated by considering 3 types of events: GPIbα diffusion, GPIbα-von Willebrand factor (vWF) bond formation, and breakage...